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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HSPD1 All Species: 59.39
Human Site: S383 Identified Species: 87.11
UniProt: P10809 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P10809 NP_002147.2 573 61055 S383 E Q L D V T T S E Y E K E K L
Chimpanzee Pan troglodytes XP_001169030 573 61022 S383 E Q L D V T T S E Y E K E K L
Rhesus Macaque Macaca mulatta XP_001082397 576 61283 S383 E Q L D V T T S E Y E K E K L
Dog Lupus familis XP_536016 573 60977 S383 E Q L D I T T S E Y E K E K L
Cat Felis silvestris
Mouse Mus musculus NP_034607 573 60937 S383 E Q L D I T T S E Y E K E K L
Rat Rattus norvegicus P63039 573 60937 S383 E Q L D I T T S E Y E K E K L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZL72 573 60954 S383 E Q L E V T T S E Y E K E K L
Frog Xenopus laevis NP_001083970 579 61616 S383 D Q L E T T S S E Y E K E K L
Zebra Danio Brachydanio rerio NP_851847 575 61178 S383 E Q L E S T N S D Y E K E K L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O02649 573 60790 S379 D Q I E D T T S E Y E K E K L
Honey Bee Apis mellifera XP_392899 570 60394 S378 D Q I A N T T S D Y E K E K L
Nematode Worm Caenorhab. elegans P50140 568 60082 S374 D E I E Q S T S D Y E K E K L
Sea Urchin Strong. purpuratus XP_795205 586 62222 S389 E Q V E N T N S E Y E R E K L
Poplar Tree Populus trichocarpa
Maize Zea mays Q43298 576 60917 S391 S A V E N S T S D Y D K E K L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P29197 577 61262 S388 S A I E L S T S D Y D K E K L
Baker's Yeast Sacchar. cerevisiae P19882 572 60733 N380 S I D I T T T N S Y E K E K L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 97.5 98 N.A. 97.5 97.5 N.A. N.A. 94 89.4 87.3 N.A. 74 74.6 71 74.9
Protein Similarity: 100 100 98.7 98.9 N.A. 98.2 98.2 N.A. N.A. 97.7 94.9 94.4 N.A. 86.3 86 82.3 87.3
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. N.A. 93.3 73.3 73.3 N.A. 73.3 66.6 53.3 66.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 93.3 86.6 N.A. 93.3 86.6 93.3 86.6
Percent
Protein Identity: N.A. 58.3 N.A. 57.8 55.6 N.A.
Protein Similarity: N.A. 76.9 N.A. 76.4 73.3 N.A.
P-Site Identity: N.A. 46.6 N.A. 46.6 53.3 N.A.
P-Site Similarity: N.A. 80 N.A. 86.6 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 13 0 7 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 25 0 7 38 7 0 0 0 32 0 13 0 0 0 0 % D
% Glu: 57 7 0 50 0 0 0 0 63 0 88 0 100 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 7 25 7 19 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 94 0 100 0 % K
% Leu: 0 0 57 0 7 0 0 0 0 0 0 0 0 0 100 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 19 0 13 7 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 75 0 0 7 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % R
% Ser: 19 0 0 0 7 19 7 94 7 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 13 82 82 0 0 0 0 0 0 0 0 % T
% Val: 0 0 13 0 25 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _